Spravato® (esketamine) treatment works fast
Break the cycle of Treatment-Resistant Depression with the first FDA-approved nasal spray for adults who need a new path forward. Administered with compassion at Phoenix’s premier Integrated Medical practice.

What Spravato® is and how it works
SPRAVATO® (esketamine) is an FDA-approved nasal spray, a form of ketamine that acts on the brain differently than traditional antidepressants. It's designed for adults with treatment-resistant depression who haven't found relief through standard medications.


Is Spravato right for you?
Spravato may be appropriate if you've tried multiple antidepressants without adequate improvement or if you're experiencing acute suicidal thoughts that need immediate attention. Our providers evaluate each patient individually to determine if this treatment fits your specific situation.
Treatment-resistant depression
TRD occurs when depression persists despite trying at least two different antidepressants at adequate doses. Spravato offers hope for those who've exhausted conventional options and need a new approach.
Acute suicidal ideation
When suicidal thoughts emerge suddenly, Spravato's rapid onset can provide critical relief. The medication works within hours or days, not weeks, making it valuable during mental health crises.
Why Spravato works
Fast-acting relief when traditional antidepressants fall short
Rapid symptom relief
Spravato reaches the brain within hours, not weeks like standard medications.
Monitored in-clinic administration
Our providers oversee each treatment session, adjusting care as needed for your response.
Adjunct to ongoing therapy
Spravato works best alongside counseling and medication management for lasting results.
Your treatment journey
We guide you through each phase with care and expertise
FAQ
Common questions about Spravato treatment, safety, and what to expect during your care at Trinity Integrated Medicine.
Yes. The FDA approved Spravato for treatment-resistant depression and acute suicidal ideation after rigorous clinical trials. Our team monitors you closely during each session to manage any side effects.
You'll receive the nasal spray in our office under supervision. Sessions last two to three hours, including observation time. You'll need someone to drive you home afterward.
Common side effects include dizziness, dissociation, and nausea, which typically resolve within hours. Serious side effects are rare when administered in a medical setting with proper monitoring.
Many insurance plans cover Spravato, though coverage varies. Our team verifies your benefits before starting treatment and helps navigate any authorization requirements.
The induction phase typically involves twice-weekly sessions for four weeks, followed by maintenance sessions. Your provider tailors the schedule to your response and needs.
Still have questions?
Our team is here to discuss Spravato and your treatment options.
Ready to explore Spravato?
Schedule a consultation with one of our providers to discuss whether this treatment is right for you.
